Demyelination and axonal preservation in a transgenic mouse model of Pelizaeus‐Merzbacher disease
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چکیده
منابع مشابه
Demyelination and axonal preservation in a transgenic mouse model of Pelizaeus-Merzbacher disease
It is widely thought that demyelination contributes to the degeneration of axons and, in combination with acute inflammatory injury, is responsible for progressive axonal loss and persistent clinical disability in inflammatory demyelinating disease. In this study we sought to characterize the relationship between demyelination, inflammation and axonal transport changes using a Plp1-transgenic m...
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ژورنال
عنوان ژورنال: EMBO Molecular Medicine
سال: 2010
ISSN: 1757-4676,1757-4684
DOI: 10.1002/emmm.200900057